Research Facilities Resources Business Contacts FAQ

FREQUENTLY ASKED QUESTIONS

What is hepatitis C?

Who is at risk?

What are the symptoms of hepatitis C?

How soon do symptoms appear?

 How do you get it?

How can you avoid getting it?

How can you find out if you are infected?
 

What is hepatitis C?

This is a liver disease caused by hepatitis C virus  infection . Once called non-A and non-B hepatitis, the existence of  HCV was first identified in the mid 1970’s. It wasn’t until 1989, however, that the test for specific antibodies to the virus became available, permitting routine testing. About 36,000 Americans contract HCV each year. It is a more frequent cause of chronic liver disease than hepatitis B. While it was believed originally that half the cases of acute hepatitis C become chronic, it is now estimated that may range between 55% and 85% and some may develop cirrhosis. Some individuals with cirrhosis may also develop cancer of the liver called hepatoma. Studies are being conducted to identify those who will benefit from currently available treatment. New treatment strategies are also being developed.

GO TO TOP


 
 
 

 

Who is at risk?
People who are at risk of acquiring hepatitis C include anyone who had a transplant, blood transfusion or used blood products prior to July, 1992, IV drug users, patients on hemodialysis and hemophilia patients. Such individuals should be tested for hepatitis C. Body-piercing, tattooing and sharing straws when snorting cocaine are also risk factors. However, an estimated 10% or more have no identifiable history of exposure to the virus, and about 15-45% clear the virus by themselves.

GO TO TOP

What are the symptoms of hepatitis C?

The typical symptoms are abdominal discomfort, loss of appetite, nausea, vomiting, fatigue, and weight loss, and sometimes yellowing of the skin and eyes (jaundice).  Symptoms can range from mile to severe.  75% of infected persons may have no symptoms.  Once infected, most persons carry the virus in their blood for many years, or for life.

GO TO TOP

How soon do symptoms appear?

If a person has  symptoms, they can appear anywhere from 2 weeks to 6 months after exposure with an average of 6 to 9 weeks.

GO TO TOP

How do you get it?

The virus is present in the blood, and certain other body fluids.  Spread is only known to occur when blood from an infected person enters a break in the skin and mucous membranes (like the lining of the mouth and vagina or the white of the eye), and infrequently through sexual exposure.

Spread to the following groups is possible if there is contact with a person infected with 

hepatitis C:

 
  • IV drug users – by sharing blood contaminated needles.
  • · Tattoo or body piercing customers – if non-sterile needles are used
    · Health care workers with frequent blood contact.
    · Some sexual or intimate partners – the risk of transmission between steady (monogamous)          practices for persons with a steady sexual partner.  However persons with multiple partners may be at somewhat higher risk of becoming infected, and practicing “safe sex” is indicated for the prevention of many sexually transmitted diseases.
    · Blood transfusion recipients – where the blood donor was infected with hepatitis C virus.  This type of spread became very uncommon when blood banks began discouraging persons at risk for HIV and hepatitis from donating blood in 1983.  The risk has been reduced further now that blood banks screen all donors for hepatitis C antibody and destroy any blood that tests positive.
    Other person to whom hepatitis C may infrequently be spread:
    · Infants born to mothers who are hepatitis C carriers.
    · Mentally retarded residents of institutions who have contact with hepatitis C carriers – through biting and combative behaviors, sexual contact, and occasionally sharing of personal items such as blood contaminated tooth brushes and wash cloths.
    Hepatitis C virus is not spread through casual contact or in typical school, office, or food service setting.  It is not spread by coughing, sneezing, or drinking out of the same glass. 
    GO TO TOP

    How can you avoid getting it?

    · When handling blood-contaminated objects or surfaces, wear plastic, latex, or rubber gloves.  Always wash hands thoroughly with soap and water if they become contaminated with blood.  Wash blood contaminated surfaces with soap and water, and then disinfect with a 10% bleach solution

    ·  Disposable blood-contaminated items should be bagged before discarding.
    · Avoid sharing personal items such as washcloths, razors, toothbrushes, and gum
    · Prevent aggressive (biting) behavior.
    · Health care personnel need to wear gloves when caring for patients with bleeding or oozing wounds, or when in contact with other bodily secretions.  Do NOT recap needles; dispose of needles in sharps containers. 
    · Dishes, eating utensils, toilet facilities, swimming pools and water fountains require only the usual recommended cleaning procedures and are NOT sources of hepatitis C exposure.


    GO TO TOP
     

    How can you find out if you are infected?

    Have a blood test (ELISA or RIBA) to detect hepatitis C antibody, or a blood test to detect the virus, polymerase chain reaction (PCR). 

    A positive blood test for the hepatitis C antibody can mean the following:

    1. Recent or Acute Infection – this diagnosis is usually made if a person has typical signs and symptoms of hepatitis, blood tests showing markedly elevated liver function, and negative tests for hepatitis A and B.
    2. Chronic Carrier – A chronic carrier is a person who has been infected for more then 6 months and who continues to carry the virus.  The carrier usually does not have obvious signs or symptoms of hepatitis although there may be vague symptoms and abnormal liver function tests.  Over time the virus may cause serious liver damage (cirrhosis or live cancer), and carriers should be followed closely by a physician.  The carrier patient may be referred to a doctor specializing in the treatment of liver disease.  Current method of treating chronic hepatitis C infection are not effective for all patients, though some patients will benefit from treatment with alpha-interferon B and other anti-viral medications.  Vaccination again hepatitis A and hepatitis B viruses should be considered for persons who are chronically infected with hepatitis C.
    3. Immunity – Once infected, most people do not develop immunity to the virus.
    4. False Positive Test – The blood test in not 100% accurate.  Sometime the test is positive even though the person has never been infected with hepatitis C. Use of a different test may indicate that the initial test was not a true positive, and that the person does not have hepatitis C.
    5. False Negative Test – In some persons, it may take several months after the onset of the illness for the hepatitis C antibody test to become positive, although these persons may have abnormal liver function tests and symptoms of hepatitis.  The test may be positive if re-run at a later time.


    GO TO TOP
     


Go to Home Page
to Home Page

Web site questions and comments to webmaster

Copyright California Institute of Molecular Medicine. All Rights Reserved.